Últimas noticias

A continuación se muestran las últimas novedades sobre investigaciones, eventos, actividades y descubrimientos que se llevan a cabo en el Instituto de Productos Naturales y Agrobiología.

Publicaciones recientes

Image
Saharan Dust Events

Saharan Dust Events in the Dust Belt -Canary Islandsand the Observed Association with in-Hospital Mortality of Patients with Heart Failure

Recent studies have found increases in the cardiovascular mortality rates during poor air quality events due to outbreaks of desert dust. In Tenerife, we collected (2014–2017) data in 829 patients admitted with a heart failure diagnosis in the Emergency Department of the University Hospital of the Canaries. In this region, concentrations of PM10 and PM2.5 are usually low (~20 and 10 g/m3), but they increase to 360 and 115 g/m3, respectively, during Saharan dust events. By using statistical tools (including multivariable logistic regressions), we compared in-hospital mortality of patients with heart failure and exposure to PM10 and PM2.5 during dust and no-dust events. We found that 86% of in-hospital heart failure mortality cases occurred during Saharan dust episodes that resulted in PM10 > 50 g/m3 (interquartile range: 71–96 g/m3). A multivariate analysis showed that, after adjusting for other covariates, exposure to Saharan dust events associated with PM10 > 50 g/m3 was an independent predictor of heart failure in-hospital mortality (OR = 2.79, 95% CI (1.066–7.332), p = 0.03). In conclusion, this study demonstrates that exposure to high Saharan dust concentrations is independently associated with in-hospital mortality in patients with heart failure.

Dominguez-Rodriguez, Alberto; Baez-Ferrer, Néstor; Rodríguez, Sergio; Avanzas, Pablo; Abreu-Gonzalez, Pedro; Terradellas, Enric; Cuevas, Emilio; Basart, Sara

Journal of Clinical Medicine 9(2): 376 (2020)
Image
The importance of threatened host plants for arthropod diversity: the fauna associated with dendroid Euphorbia plants endemic to the Canary and Madeira archipelagos

The importance of threatened host plants for arthropod diversity: the fauna associated with dendroid Euphorbia plants endemic to the Canary and Madeira archipelagos

The arthropod fauna associated with seven endemic dendroid Euphorbia was sampled and studied in the Canary and Madeira archipelagos. The stem-diameter of the plants was considered, along with their genetic affinity, habitat and number of localities and islands where present. The arthropod assemblages and richness found on each Euphorbia species were statistically analysed, to determine which variables influenced the survey results. A total of 179 arthropod species were found, identified, and classified into characteristic or accompanying fauna, according to their relationship with the plants and their types of diet. Faunal assemblages and arthropod species richness differed among the Euphorbia species, each thus showing a strong and almost unique host relationship. Species richness increased with the architectural complexity of the host-plant species and number of localities and islands where present. The similarity of faunal assemblages was mainly related to stem diameter. Among diet types, a great number of exclusive and/or endemic taxa associated with this plant genus were xylophages. Our survey revealed that rich arthropod communities are associated with the genus Euphorbia, especially on its rare endangered species, and highlights the need to protect their host plants. This in turn will contribute to the conservation of their arthropod communities and their ecosystem functions.

Hernández-Teixidor, David; Santos, Irene; Suárez, Daniel; Oromí, Pedro

Journal of Insect Conservation (2020)
Image
Alkane-, alkene-, alkyne-γ-lactones and ryanodane diterpenes from aeroponically grown Persea indica roots

Alkane-, alkene-, alkyne-γ-lactones and ryanodane diterpenes from aeroponically grown Persea indica roots

This work presents the study of the roots of the Macaronesian paleoendemism Persea indica (L.) Spreng. The root biomass of this protected tree species has been produced by soil-less aeroponic culture under controlled environment. This system has important advantages over traditional plant production techniques because it provides opportunities to optimize the yield of metabolite production under well-controlled conditions, thereby facilitating commercial-scale production of bioactive compounds. Thus, for the first time a study of this type has permitted the isolation from the roots of seven undescribed dextrorotatory lactones: the alkane-γ-lactones (+)-majoranolide and (+)-dihydromajorenolide, the alkene-γ-lactones (+)-majorenolide and (+)-majorenolide acetate, and the alkyne-γ-lactones, (+)-majorynolide, (+)-majorynolide acetate and (+)-isomajorynolide. In addition, thirteen known compounds were also isolated including two possible avocadofurane precursors, avocadynone acetate and avocadenone acetate, the monoterpene esters cis- and trans-p-coumarate of (−)-borneol, and the ryanoid diterpenes cinnzeylanone, anhidrocinnzeylanine, cinnzeylanine, cinnzeylanol, epiryanodol, perseanol, cinncassiol E, perseaindicol and secoperseanol. The configuration at C-14 de two ryanodane diterpenes has also been revised in this work. Furthermore, (−)-borneol cis-p-coumarate has showed to be insecticidal to S. littoralis and cytotoxic to insect (Sf9) cells, (+)-majorenolide antifeedant to aphids and cytotoxic to Sf9, cinnceylanol antifeedant and insecticidal to S. littoralis, and (+)-majorynolide (2), insecticidal against S. littoralis, cytotoxic to Sf9 and nematicidal, suggesting a defensive role for these compounds.

Fraga, Braulio M.; Díaz, Carmen E.; Bolaños, Patricia; Bailén, María; Andrés, María Fe; González-Coloma, Azucena

Phytochemistry 176: 112398 (2020)

Blog

El blog del IPNA recoge artículos de divulgación sobre los diversos proyectos de investigación desarrollados en el centro, avances en la ciencia y otros temas de interés sobre cultura científica.