The research activity during these years has focused on the field of free radicals and carbohydrate chemistry to obtain new compounds with high added value. This has covered both the synthetic transformations of simple and complex carbohydrates as well as the generation of radicals centered on oxygen, nitrogen and carbon and their subsequent use in intramolecular hydrogen atom transfer and β-fragmentation reactions. As a result, significant milestones have been achieved such as the radical synthesis of chiral spiroacetals from carbohydrates, the synthesis of analogues of the antitumour agent spicamycin, the synthesis of tetrameric carbopeptides with secondary structures, and the conversion of D- into L-sugars in mono- and disaccharide systems.
Currently, my research interests are focused on the radical chemistry applied to cyclodextrins. These are natural cyclic oligosaccharides of great importance in the field of supramolecular chemistry, due to their ability to encapsulate molecules in their internal cavity. Our objective is to apply simple, efficient and sustainable radical processes to form new cyclic and linear oligosaccharides, of interest to get structural diversity and complexity.
Synthetic Methodology, Free Radicals in Organic Synthesis, C-H Functionalization, β-Fragmentation, Photochemistry, Photocatalysis, Carbohydrates, Cyclodextrins.
- PhD in Chemistry, University of La Laguna (1996).
- BSc in Chemistry, specialized in Organic Chemistry, University of La Laguna (1991).
- Tenured Scientist, IPNA-CSIC (2000-present).
- Interim Tenured Scientist, IPNA-CSIC (1999-2000).
- Postdoctoral Research Fellow of the Spanish Ministry of Education and Science (MEC), IPNA-CSIC (1999).
- Marie Curie Postdoctoral Fellow, University of Oxford, UK (1997-1999).
- MEC Postdoctoral Fellow, University of Oxford, UK (1996-1997)
- MEC Predoctoral Fellow, IPNA-CSIC (1992-1995)
- Scientific Supervisor in Mass Spectrometry and Elemental Analysis Service at IPNA (2005-2019).
- Member of the Management Committee of the COST Action CM1201 "Biomimetic Radical Chemistry" (2012-2016).