Elisa de León
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Elisa Isabel De León Alonso

Científico Titular
Chemistry of Bioactive Natural and Synthetic Products
Natural Products Synthesis

After carrying out my PhD thesis at the then Institute of Organic Natural Products (IPNO/CSIC) on organoselenium chemistry, under the direction of Professor E. Suárez, I worked during the postdoc with Professor K.C. Nicolaou, synthesising anticancer analogues of endiines, and with Professor H. Rapoport on the synthesis of antiviral analogues of Sinefungin.

Since I joined the Institute of Natural Products and Agrobiology (IPNA/CSIC), I have focused my interest on the development of effective and environmentally compatible radical-based methodologies for the synthesis of potentially bioactive analogues of natural products.

I am currently responsible for a research line that modifies carbohydrates by photochemical TIH reactions promoted by 1,2-dicarbonyl systems photoexcited exclusively by visible light, in the absence of any catalyst or additive.

Research Interests

Organic Synthesis, Synthesis Methodology, Free Radicals, Photochemistry, Intramolecular Hydrogen Transfer (IHT), b-Fragmentation.

  • PhD in Chemical Sciences, University of La Laguna (1989).
  • Master's Degree, University of La Laguna (1985).
  • Degree in Chemical Sciences, speciality Organic Chemistry, University of La Laguna (1984).
Professional Experience
  • Senior Scientist at CSIC, IPNA/CSIC (1992-present).
  • Postdoctoral Fellow, Reincorporation in Spain, IPNA/CSIC (1991-1992).
  • Fulbright Postdoctoral Fellow, University of Berkeley, USA (1990-1991).
  • Fulbright Postdoctoral Fellow, the Scripps Research Institute, USA (1989-1990).
  • FPI predoctoral fellow, IPNO/CSIC (1985-1989).
  • Postgraduate fellow, Cabildo de Tenerife, IPNO/CSIC (1984-1985).
  • Director of the Department of Natural Product Synthesis (2016-2020).
  • Committee Member of R&D&I Intermediation Organizations Network in the Canary Islands (RED VALORA) (2008-2010).
  • Scientific Manager of the General Warehouse Service at the IPNA-CSIC (2003-2020).
  • Staff Representative on the IPNA Governing Board (2001-2005 and 2006-2009).
  • Member of the Spanish Royal Society of Chemistry (RSEQ).
Research IDs
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