Antonio Hernández Daranas is a structural chemist with interests in structural biology. Contributions include the publication of an experimental procedure to use Isothermal Titration Calorimetry as a valid technique for studying biologically and synthetically important low affinity systems and the use of Nuclear Magnetic Resonance (NMR) homo- and heteronuclear coupling constants together with Quantum Mechanical calculations to develop improved methodologies for structure determination of small molecules. Applications over the years were focused on the chemical study of marine organisms, in particular dinoflagellates, that resulted in the discovery and structure elucidation of several novel bioactive natural products. The study of protein-ligand interactions by NMR, calorimetry and computational simulations has been another important subject of research. A major focus of his work over recent years has been in developing more efficient structure elucidation methodologies using computational techniques and NMR spectroscopy.
NMR spectroscopy, computational chemistry, natural products chemistry, protein-ligand interactions, calorimetry.
- Bachelor of Pharmacy (1988-1993, University of La Laguna)
- Travelling Research Fellow at Univ. of Rhode Island (1996)
- Diploma in Public Health (1997-1998, National School of Public Health)
- PhD in Marine Natural Products Chemistry (1994-1999, University of La Laguna)
- Tenured Scientist, National Research Council, CSIC (2017-present)
- Scientific Director of the NMR Service at IPNA-CSIC (2017 – Present)
- Scientific Consultant in Structure Elucidation for PharmaMar S.A.(2016)
- Honorary Researcher, Imperial College London (2014-2016)
- Researcher, Institute of Bio-Organic Chemistry Antonio González, University of La Laguna (2014-2016)
- Scientific Director of the Biological Calorimetry Service of the Center of Biomedical Research of the Canary Islands (CIBICAN) (2013 – 2017)
- Member of the Editorial Board of Marine Drugs (ISSN 1660-3397) (2008 – Present)
- Scientific Director of ULL Laboratory of Toxicological Standards (2006 – 2013)
- Lecturer in Pharmaceutical Technology, Faculty of Pharmacy, University of La Laguna (2004-2013)
- Marie Curie Research Fellow, Astbury Centre for Structural Molecular Biology, University of Leeds (2000-2003)
- Fellow of the Spanish Royal Society of Chemistry
- Award for Excellence in Academic Performance in Pharmacy (1999)
- Accredited as Associate Professor by the ANECA agency (2011)
- Award for Innovation in Natural Products Research by the Specialized Group of Natural Products of the Spanish Royal Society of Chemistry (2015)